Web user interface design is not museum art that will last as is for 1000 years. Get it done, get feedback and then adapt it to make it better.
Web user interface design is not hard. It's fast, cheap and easy. Designing a web user interface can be done quickly with mocking tools like Figma or Sketch or even direct to HTML or even React components.
A web user interface is not a museum art piece that can stand the test of time. No. It is a dynamic living user interface to solve the problem at hand.
Do not obsess over what goes where. The top left has the most important content. Top navigation, bottom navigation, possibly side navigation, search and then add the main elements.
User testing and tracking tools will quickly give you feedback about how you want to change the web user interface to simplify and streamline the design.
Web user interface design is almost real-time with tools like Figma or the million HTML design kits available. Do not obsess with getting it right immediately. Get started and adapt in an agile and low-cost way.